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FR-900098 and FR-33289 antibiotics biosynthesis

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
CMP-5''-3-(aminopropyl)phosphonate + NADPH + O2 <=> CMP-5''-N-hydroxy-3-(aminopropyl)phosphonate + NADP+ + H2O 1.14.13

2-Oxophosphonobutanoate + aminated_amino_group_donor <=> DL-2-Amino-4-phosphonobutanoate + deaminated_amino_group_donor 2.6.1

CMP-5''-N-hydroxy-3-(aminopropyl)phosphonate + acetyl-CoA <=> CMP-5''-3-(N-acetyl-N-hydroxy)aminopropylphosphonate + CoA 2.3.1

FR-900098 + 2-oxoglutarate + O2 <=> FR-33289 + succinate + CO2 1.14.11

DL-2-Amino-4-phosphonobutanoate + CTP + H+ <=> CMP-5''-3-(aminopropyl)phosphonate + diphosphate + CO2 2.7.7

3-phosphonomethylmalate + H+ + acceptor <=> 2-Oxophosphonobutanoate + CO2 + reduced_acceptor 4.1.1

(R)-2-(phosphonomethyl)malate <=> 3-phosphonomethylmalate 5.4.99

CMP-5''-3-(N-acetyl-N-hydroxy)aminopropylphosphonate + H2O <=> FR-900098 + CMP + H+ 3.6.1

H+ + phosphoenolpyruvate <=> Phosphonopyruvate 5.4.2.9 phosphoenolpyruvate mutase

Phosphonopyruvate + acetyl-CoA + H2O <=> (R)-2-(phosphonomethyl)malate + CoA + H+ 2.3.3.19 2-phosphonomethylmalate synthase

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